It’s time to transform your relationship with plants
Rooted in Ayurvedic medicine, this herb is often used to reduce stress through impacting cortisol levels (stress hormone). A natural remedy for low energy levels, and helps promote alertness.
Shown to decrease anxiety in people suffering from sleeping disorders. Chemicals isolated include flavonoids, diterpenoids and phenylpropanoids. Traditionally, consumed as a dried herb, as a tea, and a tincture prepared as a dilution on a daily basis.
Quercetin is a flavonoid compound within cardamom, believed to be responsible for its powerful therapeutic effect. Research into quercetin showed lowered anxiety and depression. Used in traditional remedies for depression by grinding seeds into powder and boiling in water with tea leaves.
Chamomile was found to improve on sleep latency, night time awakenings, and fatigue severity scores. Overall chamomile is a safe herb with minimal side effects.
Muscle cramps; a specific combination of peony and liquorice (shakuyaku-kanzo-to). There is no limited standardisation. One common preparation, total glucosides of peony, is a water or alcohol extract of the root. Commonly used in combination with other herbs in traditional Chinese medicine.
Contains triterpene saponins, flavonol glycosides, methoxy flavone, and other flavonoids. A remedy for insomnia, headaches, over-activity, and nerve pain (neuralgia). Contains saponins and salicylates which are the main ingredient of aspirin. The yellow flower is antispasmodic and sedative.
Anxiolytic effects; apigenin may play a role in this activity, central nervous system (CNS) depressant activity. Hypoglycemic agent, sedative-hypnotic agent (used to reduce tension and anxiety and induce calm (sedative effect) or to induce sleep (hypnotic effect).
Used to treat migraine headache in combinations with white willow, magnesium, vitamin B6, tanacetum parthenium, 5-HTP and ginger. Used to treat opiate withdrawal. Anti-inflammatory effects. May block prostaglandin synthesis by inhibiting phospholipase, which prevents the release of arachidonic acid.
Traditionally used for the treatment of insomnia. Strongest potentiation of GABA A receptors amongst plant-based remedies. Ginseng red potentiation on GABA A receptors was higher than that of using Ginseng white. Contains ginsenosides. Hypoglycemic agent, immunomodulators, immunostimulants, adaptogens.
The whole plant is astringent, slightly diuretic, sedative, tonic and vulnerary. Used to treat wounds and as a sedative, for treating nervous disorders. It is used as a homeopathic tonic for anxiety, Very little is known about the chemistry of this plant.
Stimulates central nervous system (CNS), heart, and muscles. Guaranine (aka caffeine) is found in guarana and is identical to caffeine derived from coffee or tea. Contains varying mixtures of xanthine alkaloids other than caffeine, including cardiac stimulants theophylline, theobromine and polyphenols.
Increases force of contraction of the heart, whilst slowing the rate. Used as a traditional remedy for high blood pressure. Anxiety can produce overstimulation of the ‘fight or flight response’ causing an increase in heart rate. Major pharmacologically active components are believed to be flavonoids.
The seed oil of holy basil contains linoleic acid (52%), linolenic acid (17%), oleic acid (14%), palmitic acid (12%), and stearic acid. Antiplatelet agent, hypoglycemic agent, immunomodulators, adaptogens, stimulent (cognitive).
Hops main sedative activity lies mostly in the alpha bitter acid constituents, the main conclusions from the review were using hops in conjunction with valerian for sleep disturbances can be beneficial as it modulates the GABAergic system and melatonin receptors.
Anti-inflammatory, diuretic and haemostatic. In traditional Chinese medicine (TCM) Japanese thistle are plants that are “Cool” in nature. This means that Japanese thistle tend to help people who have too much “heat” in their body. The balance between Yin and Yang is a key health concept in TCM.
Sedative-hypnotic with anti-inflammatory properties. Induces relaxation and sedation. Decreases EEG and alertness. Used in capsules/tinctures to address anxiety. Reduces time to fall asleep, improves sleep, and reduces sleepiness at awakening (due to increased melatonin following inhalation).
Cholinergic modulation impacts memory and alertness. When given with valerian, passionflower, and butterbur can lower anxiety. Contains citronellal, neral, flavonoids, polyphenol compounds, monoterpene glycosides, and triterpenoids. Hypoglycemic, immunostimulants, and sedative-hypnotic agent.
Central nervous system (CNS) effects: The sedative effects of linden may be attributed to the volatile oils, including citral, citronellal, citronellol, eugenol, and limonene. Diuretics, Sedative-Hypnotic Agents.
GABA A potentiator. Magnolol and honokiol are bioactive compounds with sedative + hypnotic effects. Magnolol acts via the GABA A receptor increasing NREM and REM sleep. Honokiol and magnolol have a great future having demonstrated great efficacy in treating insomnia and approved for this use.
Anti-inflammatory properties found in early studies though more trials and work needed to fully understand the modes of action of the plant.
The exact effect on insomnia unknown. Sedative-hypnotic agent, diuretic. Used for heart conditions (inc heart failure, irregular heartbeat, fast heartbeat, and heart symptoms due to anxiety). Well tolerated. Motherwort, valerian, hops, and lemon balm taken before bed can improve sleep quality.
Pain: A standardized myrrh extract (MyrLiq, Biosfered S.r.l.) 200-400 mg once daily for 20 days has been used.
A multi-functional grain. Dose of vitamin B, magnesium and fibre helps neutralise stress hormone cortisol. Restorative impact on the nervous system. Historic use to address stress, anxiety, fatigue, attention deficit hyperactivity disorder (ADHD), depression, sexual lacklustre, grief and trauma.
There is no recent evidence to support specific doses of pasque flower. The fresh plant is toxic; classical doses of the dried herb were from 0.1 to 0.4 g daily.
Sedative-hypnotic agent inhibits uptake of GABA (mediation of the GABAergic system) and has an affinity for GABA A + B receptors. Dried extracts often used in combination with a range of plants targeting additional anxiety and sleeplessness pathways (i.e. valerian, hawthorn, horehound and saffron).
Anxiolytic and sedative properties, a GABA-A potentiator, similar effect on GABA-benzodiazepine receptors and useful in treatment for insomnia. May inhibit cholinesterase and have a protective effect on dopaminergic neurons. Antiplatelet agents, salicylate-containing herb & supplement.
Used in the treatment of anxiety; clinical research shows mitigation of moderate anxiety. Also used in the treatment of depression, and shown benefit in clinical research. May modulate brain serotonin by inhibiting serotonin reuptake, and altering dopamine and norepinephrine.
Modulation of GABA receptor. 5-HT(7) receptor effects: constituents bind the serotonin receptor 5-HT(7). Activity on the 5-HT(7) receptor is due to flavonoids. Effects serotonin receptor causing sedation. Anxiolytic: flavonoids may act as GABA agonists causing a sedating and anxiolytic effect.
Used for treating many disorders including sleep disturbances. Active compounds are hyperforin and hypericin; hypericin exerts its effects via monoamine oxidase inhibition, whereas hyperforin acts via the inhibition of GABA, serotonin, dopamine, L-glutamate, and norepinephrine reuptake.
Used for treatment of insomnia. May work as well as benzodiazepines in promoting natural sleep over time. Herbal hypnotic and sedative. May also have follow-on soporific effects (in stress-induced insomnia) due to shared pathways via down-regulation of neurological stimulatory activity (therefore useful for anxiety).
Clinical research remains nascent. Traditional dosage of decoction taken several times per day has been described. Interaction rating moderate; must be cautious in combination. Polyphenolic compounds can inhibit iron absorption. Drinking as tea decreased iron absorption from a meal by 59%.
Neurologic/central nervous system (CNS), sedative (hypnotic agents) and antispasmodic. Effects may be due to phthalide constituents (d-limonene, selinene). Antiplatelet agents, Cytochrome P450 1A2 (CYP1A2) Inhibitors, photosensitizers. Capsules containing 250 mg extract have been used daily.
Anxiolytic effects, but currently no high-quality studies on the medicinal applications of betony. Most dosing information based on traditional use. Used as an infusion, dried herb in boiling water, as a liquid extract or tincture. Consumed multiple times per day.