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St John’s Wort

plant

taxonomy

parts used

application

mode of action

St John’s Wort

Hypericum perforatum

Whole plant

Antidepressant and aid in sleeplessness

Used for treating many disorders including sleep disturbances. Active compounds are hyperforin and hypericin; hypericin exerts its effects via monoamine oxidase inhibition, whereas hyperforin acts via the inhibition of GABA, serotonin, dopamine, L-glutamate, and norepinephrine reuptake.